Carbon based Frustrated Lewis Pair

Frustrated Lewis pairs (FLPs) arise from the combination of Lewis acids (LAs) and bases (LBs) with un-neutralized reactivity due to the steric repulsion between these units. Common bases for FLPs found in the literature include a wide range of phosphines, amines, pyridines, N-heterocyclic carbenes (NHCs), or carbodiphosphoranes, which show compatibility with various solvents and functional groups during transformations. In contrast, the LA counterparts in FLPs are less versatile and mostly limited to perfluorinated alkyl/aryl boranes and alanes. As a result, the development of versatile and stable LAs for FLP chemistry is still highly desirable.

Thomas L. Gianetti
Assistant Professor
Department of Chemistry and Biochemistry, University of Arizona.
CSML 638, 1306 E. University Blvd., Tucson, AZ 85719
Office: +1 520 626 3609